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pentobarbital will reduce the level or effect of propafenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.Check Closely (2)pentobarbital will reduce the extent or influence of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Potent CYP3A4 inducers may minimi